Antibodies are created by the body’s immune system to counteract an unwanted, external element, such as when a pathogen of some sort—a virus, bacterium, fungus, or other foreign substance—enters the body.28 This sets off a series of reactions beginning with the body’s basic alarm system, the innate response, which is a one-size-fits-all process designed to get rid of unwanted visitors quickly. If the innate system can’t eradicate the pathogen, the next defense stage is the “adaptive response,” which tailors itself to the specific intruder, using an arsenal of white blood cells and antibodies. This takes much longer to mobilize than the innate response, ten days versus the innate system’s minutes or hours.29 Usually the collateral damage of these internal battles results in familiar flulike symptoms such as headache, fever, muscle ache, nausea, and enlarged lymph nodes.30 [Картинка: _14.jpg] An immune cell, called a phagocyte,“eating” a pathogen. • Immobility/stupor Men's Health

Oregon Trail

Following in the footsteps of pilgrims and pioneers, US‑20 takes in a little of everything during its two-lane trek from Oregon’s rugged coast to the glorious sea and sand of Cape Cod.

Sunset Highway: Saddle Mountain State Park

Running over the coastal mountains between Cannon Beach and Portland, US-26 is known as the Sunset Highway. Climbing up from the coastal plain, two miles east of US-101, our first stop is the old-growth spruce and fir forest preserved in 25-acre Klootchy Creek County Park. Until recently, among the many huge firs and spruce trees was the Seaside Giant Spruce. More than 215 feet high, almost 16 feet in diameter, the tree was snapped in two by a storm in December 2007. Safety concerns caused officials to cut down the tree, but the huge stump and fallen sections have been left in place to show how massive the old-timer really was.

About 10 miles east of US-101, an 8-mile side trip to the northeast, along well-signed Saddle Mountain Road, will lift you quickly above the frequent coastal clouds and fog. Named for a geographical saddle that sits high above the surrounding forests, Saddle Mountain State Park surrounds the highest point in the Coast Range. A very steep 2.5-mile hiking trail climbs to the summit, with opportunities to view bleeding heart, Indian paintbrush, monkey flowers, and other rare plants and wildflowers. From the 3,283-foot peak, you can often see the mouth of the Columbia River and the spine of the Coast Range. On a clear day, the panorama may include 50 miles of Pacific coastline and Mounts Hood, St. Helens, and Rainier (with more than a few ugly acres of clear-cuts in between). Ten primitive campsites (503/368-5943 or 800/551-6949, $6) are open March-October on a first-come, first-served basis; RVs should avoid this narrow road.

Klootchy Creek County Park

Saddle Mountain State Park

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